Induction of bacteriocins from Clostridium perfringens by treatment with mitomycin C.

نویسنده

  • D E Mahony
چکیده

Six of ten bacteriocinogenic strains of Clostridium perfringens were inducible by treating the cultures with mitomycin C. Induction did not occur in the continued presence of mitomycin C but only when excess mitomycin C was removed. Cell death was associated with induction of bacteriocin.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Genotyping of Clostridium perfringens isolated from broiler meat in northeastern of Iran

Clostridium perfringens is an important cause of bacterial food poisoning worldwide. The disease is caused by C. perfringens enterotoxin (CPE) encoded by cpe gene. The aim of this research was to identify the different types of C. perfringens and the presence of cpe gene in isolated bacteria from broilers’ meat marketed in retail meat shops of Mashha...

متن کامل

Occurrence of Beta2 toxigenic Clostridium perfringens isolates with different toxin types in Iran

Clostridium perfringens is an important cause of enteric diseases in both human and animals. The bacteria produce several toxins which play key roles in the pathogenesis of diseases and are classified into five toxin types, on the basis of the differential production of Alpha, Beta, Epsilon and Iota toxins. In this study a single PCR assay was developed and used for detection of cpb2 gene to id...

متن کامل

Molecular typing of toxigenic Clostridum perfringens isolated from sheep in Iran

In this research a molecular method based on polymerase chain reaction for typing of Clostridium perfringens was developed and toxin genotypes of 64 isolates from sheep and goats in Iran were determined. The PCR assays were developed for detection of alpha (cpa), beta (cpb) and epsilon (etx) toxin genes, allowing classification of the isolates into genotypes A B, C and D. The field isolates ...

متن کامل

Comparative study of ten bacteriocins of Clostridium perfringens.

Bacteriocins of Clostridium perfringens were prepared by ammonium sulfate precipitation of supernatant broth from 10 bacteriocinogenic strains. These bacteriocins were compared with respect to their ability to produce spheroplasts in a sensitive indicator strain; their inducibility; sensitivity to pH, proteolytic enzymes, and boiling; and their effect on macromolecular synthesis. Two bacterioci...

متن کامل

Typing of Toxigenic Isolates of Clostridium perfringens by Multiplex PCR in Ostrich

Clostridium perfringens is an important pathogen that provokes numerous different diseases. This bacterium is classified into five various types, each of which capable of causing a distinct disease. There are various methods for the bacterial identification, many are labor-intensive, time-consuming, expensive and also show low sensitivity and specificity. The aim of this research was to identif...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 11 6  شماره 

صفحات  -

تاریخ انتشار 1977